Announcements

Published Online: September 14 2006 | ss20060908a1
Keywords: CELL BIOLOGY | plant | Arabidopsis | stoma | innate immune response | Caenorhabditis elegans worms | protein folding | protein misfolding | chronic neurological diseases | pathogenesis

Holding your breath

Lin PU
Call for reviews for Scidea Sketch...CELL BIOLOGY

 

 

Scidea TOS
tos20060914

Cell 126, 969-980 (2006).  Cell Press 8 September 2006 | Article Abs |

Holding your breath 

 

Take a deep breath and hold it longer; use one hand to pinch your nose shut…you will have to choose a way to hold yourself underwater or escape from a heavy smoke. Surprisingly, a famous model plant of Arabidopsis also can do like people. Evidence found by researchers from Michigan State University shows that this plant can close its stomas for safe when the stomatal guard cells sense pathogenic bacteria…

 

SEM image © Jürgen Berger-Wildtype Arabidopsis thaliana plant and the SEM image of the flower
Wildtype Arabidopsis thaliana plant and the SEM image of the flower
Scanning electron microscopy image, artificially coloured. Arabidopsis is approximately 5 mm in size.

SEM image © Jürgen Berger, Electron Microscopy Unit, Max Planck Institut
Source:
http://ec.europa.eu/research/quality-of-life/arabidopsis.html
Reproduced by Scidea Sketch 2006 www.ScideaNews.com 

 

Scidea TOS
tos20060914

Science 311. 1471-1474 (2006). Science 10 March 2006 | Article Abs |

 

Crazy folding

 

A protein is a long polymer of amino acids whose sequence is determined by the genetic code of DNA. If under unfavorable conditions, proteins misfolding (or unfolding) and aggregating will cause numerous human diseases. Recently, by introducing a few of misfolded polyglutamine proteins, researchers from RIBR of Northwestern University unexpectedly killed their lab's Caenorhabditis elegans worms. Should this fatal misfolding be an alternative pathway for understanding the pathogenesis of chronic neurological diseases?
ScideaNews.com-ManiacProtein2006

maniac protein 2006 
Credit: Scidea Art 2006 Source: www.ScideaNews.com

* Lin Pu is in the Physics Department of Nanjing University, Nanjing 210093, CHINA.

 

References

 

1

Melotto, M., Underwood, W., Koczan, J., Nomura, K., and He S. Y. Plant Stomata Function in Innate Immunity against Bacterial Invasion. Cell 126, 969-980 (2006).   Cell Press 8 September 2006 | Article Abs |
2Gidalevitz, T., Ben-Zvi, A., Ho, K. H., Brignull, H. R., Morimoto,R. I. Progressive Disruption of Cellular Protein Folding in Models of Polyglutamine Diseases. Science 311. 1471-1474 (2006)   Science 10 March 2006 | Article Abs |

 

 

 

Comments 

 

Scidea Sketch calls for in-depth review of these articles. As to Refs. 2, we are especially interesting in why certain misfolded protein structure has a fatal power.


ISSN: 1992 - 8548